Allergic diseases of the skin and drug allergies – 2024. Autoserum therapy in autologous serum skin test positive patients of chronic spontaneous urticaria
نویسنده
چکیده
Background Chronic spontaneous urticaria (CSU) patients demonstrate functional autoantibodies against high affinity receptors of IgE (FcerI). Autologous serum skin test(ASST)is mostly used in chronic spontaneous urticaria to show its autoreactivity. ASST positive patients represent a severe group which can be benefited from autoserum therapy (AST). So, aim of our study is to evaluate the efficacy of autoserum therapy in ASST positive patients.
منابع مشابه
Evaluation of the utility of autologous serum skin test and the efficacy of autologous serum therapy in chronic spontaneous urticaria
Background: Autologous serum skin test (ASST) evaluates the presence of any serum histamine-releasing factors and histamine-releasing autoantibodies. Autologous serum therapy (AST) is a therapy in which repeated injections of autologous serum are administered intramuscularly for treatment of chronicspontaneous urticaria (CSU). The aim of this study is to evaluate the advantages and compare the ...
متن کاملAllergic diseases of the skin and drug allergies – 2031. Effectiveness of autologous serum therapy in patients of chronic urticaria: a randomized, single-blind, controlled trial
Methods Patient blind, parallel group, randomised, controlled study of two study arm. 54 patients were given AST (GroupA) and control group of 57 patients given injection normal saline (placebo) (GroupB). AST/Placebo was given every week for 9 weeks and then followed-up for another 3 weeks. Levocetrizine was advised to be taken SOS in both groups. AU was diagnosed by autologous serum skin test....
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INTRODUCTION The basophil activation test showing CD63 up regulation could be a specific and sensitive in vitro complementary text to the in vivo autologous serum skin test for the activity assessment of the patients suffering autoimmune chronic spontaneous urticaria. The aim of this study is to define the basophil activation test as a useful tool in clinical practice in order to identify those...
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